Figure 3.

Pathway enrichment analysis based on single-nucleotide polymorphism (SNP) associations to intrinsic and delta physical working capacity at a heart rate of 150 beats/min (iPWC150 and dPWC150, respectively). A: pathways identified in common by GSASNP2 and Pascal for iPWC150-associated SNPs. The dendrogram was arranged by the extent of gene overlap between pathways. The enrichment P values for each pathway in GSASNP2 and Pascal are indicated in the table to the right of the dendrogram. B: dendrogram of common enriched pathways based on dPWC150-associated SNPs. Pathway P values in GSASNP2 and Pascal are indicated to the right of each pathway. KEGG, Kyoto Encyclopedia of Genes and Genomes.