Author response image 2. ScRNA-seq shows that expression of IFN target genes increases in tumors compared to normal skin and precursor lesions.

Mitfa:BFP⁺ melanocytes were sorted via FACS from normal skin, an early melanoma, and an advanced melanoma and 10X single-cell RNA-seq was performed. Data was analyzed using Seurat and cell types were called based on gene expression signatures. Depicted here are violin plots of several IFN target genes in melanocytes across the three stages.