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. 2024 Apr 29;16(6):1427–1450. doi: 10.1038/s44321-024-00072-8

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ applies to the data associated with this article, unless otherwise stated in a credit line to the data, but does not extend to the graphical or creative elements of illustrations, charts, or figures. This waiver removes legal barriers to the re-use and mining of research data. According to standard scholarly practice, it is recommended to provide appropriate citation and attribution whenever technically possible.

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Figure EV3 — (A–E) Single values, mean and SEM of GFP-positive tissue measured by immunohistochemistry in the liver (A), lung (B), spleen (C), heart (D) or kidney (E) of 8-week-old mice analyzed 10 days after i.v. administration of VSV.G-LV or GP64-LV at 4e10 TU/kg (n = 6 mice per group), or left untreated for background signal evaluation (n = 3). Kruskal–Wallis test with Dunn’s multiple comparison test. (F) Representative anti-GFP immunohistochemistry images of liver, brain, heart, kidney, lungs, spleen of mice treated with GP64-LV or VSV.G-LV, as indicated, analyzed in (A–E). Scale bar: 300 µm. (G) Higher magnification of liver and spleen sections shown in (F). Orange arrows indicate GFP-positive endothelial cells, identified by morphology. Scale bar: 100 µm.