Table 2.

The variables of CKD patients in both groups

Variables	Group	N	Baseline	After 3 months intervention	p value*	Changes **	p value ***
SBP (mmHg)	1	36	145 [140, 160]	130 [120, 140]	< 0.001	17.5 [15, 23.8]	0.001
	2	36	145 [140, 163.8]	140 [130, 150]	< 0.001	10 [10, 15]
DBP (mmHg)	1	36	95 [90, 100]	80 [76.3, 83.8]	< 0.001	15 [10, 18.8]	0.009
	2	36	90 [85, 95]	80 [80, 90]	< 0.001	10 [5, 15]
GFR (ml/min/1.73m²)	1	36	67.35 [63.1, 73.9]	68.05 [56.3, 78.8]	0.607	3.65 [-7.7, 9.4]	0.906
	2	36	66.40 [63.4, 76.9]	69.75 [58.6, 78.4]	0.879	5 [-9.3, 9.2]
Upr24hr (mg)	1	36	150 [93.2, 220]	117.5 [77.3, 160.3]	0.109	10.50 [-25.8, 78.8]	0.919
	2	36	137.50 [102.3, 307.5]	142.50 [101.5, 235]	0.311	-2 [-25, 53.8]
Ualb24hr (mg)	1	36	34 [20.9, 56]	23.5 [15.1, 31]	0.017	5 [-1.8, 20.5]	0.386
	2	36	26.70 [20.5, 61.5]	28.50 [20.2, 47]	0.460	-0.35 [-5.2, 18.6]
Bun (mg/dL)	1	36	21 [18, 26.6]	22 [17.5, 32.5]	0.106	-1.5 [-6.2, 2.8]	0.543
	2	36	18 [15, 27.87]	21 [17, 32]	0.042	-2.5 [-12.6, 3]
Cr(mg/dL)	1	36	0.98 [0.9, 1.1]	1 [0.9, 1.2]	0.244	-0.04 [-0.1, 0.09]	0.690
	2	36	1 [0.9, 1.1]	1 [0.9, 1.2]	0.197	-0.1 [-0.1, 0.1]
Na (mEq/L)	1	36	140 [138.1, 143.8]	139 [138.1, 140.1]	0.184	1.1 ± 4.7	0.161
	2	36	139.4 [137, 142.8]	140 [138, 142.8]	0.231	-0.7 ± 5.7
K (mEq/L)	1	36	4.05 [3.7, 4.3]	4.7 [4, 4.8]	0.182	-0.2 [-0.38, -0.2]	0.113
	2	36	4.1 [4, 4.6]	4.5 [4, 4.8]	0.385	0.1 [-0.3, 0.6]
Cholesterol (mg/dL)	1	36	170 [151.3,191.5]	173 [145.3, 196.8]	0.540	2.5 [-7.8, 12.5]	0.002
	2	36	162 [145, 186.7]	147.50 [130, 168]	< 0.001	17 [5.3, 24.8]
TG (mg/dL)	1	36	179 [152, 220]	178 [153, 210.3]	0.919	-10 [-21.3, 27]	0.011
	2	36	163.5 [140.3, 186.8]	144 [123, 163]	< 0.001	13 [7.3, 26.3]
LDL-C (mg/dL)	1	36	85 [78, 99.5]	88 [77, 109.5]	0.322	-2.4 [-12.8, 7]	0.104
	2	36	89 [75.5, 98.3]	82 [75, 95]	0.266	6.5 [-13.8, 22.8]
HDL(mg/dL)	1	36	45 [37.9, 52.8]	40.45 [36, 49]	0.139	3.5 ± 13.8	0.823
	2	36	45.5 [41, 54]	43 [37, 49]	0.105	4.3 ± 13.7

Group 1= control and group 2 =HS; *: Mann-Whitney U test; **: Changes from baseline to month 3; ***: T-test or Mann-Whitney U test. CKD: chronic kidney disease; SBP: Systolic blood pressure; DBP: diastolic blood pressure; GFR: glomerular filtration rate; HDL-C: high-density lipoprotein cholesterol; TG: triglycerides; LDL-C: low-density lipoprotein cholesterol; BUN: Blood urea nitrogen; Cr: Creatinine; K: Potassium; Na: sodium; Upr24hr= 24 hr urine protein; UAlb24hr: 24 hr urinary albumin; SD=standard deviation; BMI: Body mass index. Median [interquartile range] for non-normally distributed variables, and means ± standard deviations for normally distributed continuous variables.