Table 1.

Relevance of Testing Paradigms to Disease Stage

	Ready (For Current Use or within the Next 1–2 Years)	Promising (Unmet, but Defined Research Needs That Can Be Accomplished within the Next 5 Years)	Potential (Unmet Research Needs that Will Need >5 Years to Accomplish)
Preclinical		Flicker ERG OFA
Early-stage clinical disease∗		Contrast sensitivity LLVA Flicker ERG	OFA
Mid-stage clinical disease∗	BCVA	Contrast sensitivity LLVA Flicker ERG	OFA
Late-stage clinical disease∗	BCVA	Contrast sensitivity LLVA SAP

BCVA = best-corrected visual acuity; ERG = electroretinogram; LLVA = low luminance visual acuity; OFA = objective field analyzer; SAP = static automated perimetry.

^∗Stage of disease defined based on the amount of visual acuity loss.