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. 2024 Apr 15;13(6):1055–1066. doi: 10.1002/psp4.13141

FIGURE 3.

FIGURE 3

Exposure–safety analyses. Logistic regression for (a) grade ≥2 peripheral neuropathy, (b) grade ≥3 anemia, (c) grade ≥3 thrombocytopenia, versus acMMAE AUC, and (d) grade ≥3 neutropenia, (e) grade ≥3 febrile neutropenia, (f) grade ≥3 infections/infestations, (g) grade ≥3 anemia, and (h) grade ≥3 thrombocytopenia, versus unconjugated MMAE AUC. Dashed vertical lines show bounds of exposure groups. ac, antibody‐conjugated; AUC, area under the concentration–time curve; MMAE, monomethyl auristatin E.