TABLE 3.

Amino acid changes between isolates from the immunodeficient patient and Sabin 3 in the nonstructural region

Protein	Amino acid	Amino acid in strain:
		Sabin 3	H36	H136	H307	H391	H442	H480	H637
2A	41	Val	—a	—	—	Ile	Ile	Ile	Ile
	101	His	—	—	—	Tyr	—	Tyr	Tyr
2B	88	Thr	—	—	Ile	—	—	—	—
2C	33	Arg	—	—	Lys	Lys	Lys	Lys	Lys
	35	Arg	—	—	Lys	—	—	—	—
	103	Lys	—	Arg	Arg	Arg	Arg	Arg	Arg
	263	Ala	—	—	Ser	—	—	—	—
	268	Thr	—	—	Met	Met	Met	Met	Met
	270	Lys	—	—	—	Glu	Glu	Glu	Glu
	295	Lys	—	—	—	Arg	Arg	Arg	Arg
	311	Ile	—	—	—	Val	Val	Val	Val
	318	Ser	—	—	—	—	Phe	—	—
3A	12	Ile	—	—	—	—	—	Val	Val
	86	His	—	—	—	—	—	Gln	Gln
VPg	18	Ala	—	Thr	Thr	Thr	Thr	Thr	Thr
3C	16	Val	Ile	—	—	—	—	—	—
	51	Asp	—	—	Glu	Glu	Glu	Glu	Glu
	60	Lys	—	—	—	Arg	Arg	Arg	Arg
	74	Ile	Val	—	—	—	—	—	—
	131	Ile	Thr	Thr	Thr	Thr	Thr	Thr	Thr
3D	4	Gln	—	His	His	His	His	His	His
	52	Thr	—	—	—	—	—	Ala	Ala
	147	Ala	—	—	Thr	Thr	Thr	Thr	Thr
	158	Val	—	—	—	—	—	Ile	Ile
	166	Thr	—	—	—	—	—	—	Ala
	170	Gln	Leu	—	—	—	—	—	—
	176	Arg	—	Lys	—	—	—	—	—
	200	Arg	Lys	—	Lys	—	—	—	Lys
	421	Leu	—	—	—	—	—	—	Phe
	501	Ile	—	Leu	Leu	Leu	Leu	Leu	Leu

^a—, same as in Sabin 3.