TABLE 5.
Reactivity of isolates from the immunodeficient patient with monoclonal antibodies specific for different antigenic sites of Sabin 3
| Strain | Reactivity with antibody toa:
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Site 1
|
Site 2
|
Site 3
|
Site 4
|
||||||||
| 134 | 194 | 204 | 472 | 838 | 877 | 880 | 882 | 138 | 885 | 1281 | |
| Sabin 3 | + | + | + | + | + | + | + | + | + | + | + |
| H36 | + | + | + | + | + | + | + | + | + | + | + |
| H136 | + | + | + | + | − | − | − | − | − | − | + |
| H307 | + | + | + | + | + | + | + | + | − | − | + |
| H391 | + | + | + | + | + | + | + | + | − | − | − |
| H442 | + | + | + | + | + | + | + | + | − | − | − |
| H480 | + | + | + | + | + | + | + | + | − | − | − |
| H637 | + | + | + | + | − | − | − | + | − | − | − |
a
+ and −, neutralization or not, respectively, of infection of HEp-2C cells with 100 PFU of virus using a 1:50 dilution of antibody, as described in reference 29.