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. 2024 May 17;13(10):e033328. doi: 10.1161/JAHA.123.033328

Table 4.

Reduction in LDL‐C by Baseline LDL‐C

Baseline LDL‐C, mg/dL Number of users reduced LDL‐C, n (%) Baseline LDL‐C, mean (SEM) Follow up LDL‐C, mean (SEM) Mean reduction (SEM) Percent reduction, mean (SEM)
Overall 665 (52.6) 106 (1.0) 101 (1.0) −26.1 (1.2) −20.8 (0.7)
LDL‐C <100 255 (42.9) 75.9 (0.7) 80.6 (1.1) −13.4 (0.7) −17.3 (0.9)
LDL‐C 100–159 331 (58) 125 (0.7) 117 (1.3) −26.2 (1.2) −20.3 (0.9)
LDL‐C 160 to–189 54 (79.4) 172 (1.1) 133 (4.8) −52.3 (4.7) −30.1 (2.7)
LDL‐C ≥190 25 (80.6) 214 (7.0) 140 (11.4) −97.6 (15.3) −42.9 (4.8)
LDL‐C ≥160 79 (79.8) 185 (3.0) 135 (4.8) −66.6 (6.2) −34.2 (2.5)

Negative value represents reduction in LDL‐C. Baseline LDL‐C, follow‐up LDL‐C, and mean reduction values are reported in units of mg/dL. A total of 22.2% of users achieved reduction to LDL‐C <70 mg/dL. The cholesterol cohort was composed predominantly (>90%) of users who imported cholesterol values from a connected electronic health record. Hello Heart has since launched an easier way to connect electronic health records. LDL‐C indicates low‐density lipoprotein cholesterol.