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. 2024 May 3;13(9):e032172. doi: 10.1161/JAHA.123.032172

Figure 7. Infliximab‐mediated immune modulation alters the cytokine and cellular profile of the infarct bed.

Figure 7

Blood was collected from the ostium of the great cardiac vein 3 days after myocardial infarction. A through J, Cytokine profiling was distinguished with respect to interleukin‐2, ‐4, ‐10, ‐12, and ‐18 activity in infliximab‐treated (n=4) vs untreated pigs (n=3). K, Quantitation of cardiac troponin I levels was lower in infliximab‐treated (n=4) vs untreated (n=3) animals (41.72±7.34 pg/mL vs 58.11±10.75 pg/mL; P<0.05). Asterisks indicate statistical significance. GM‐CSF indicates granulocyte‐macrophage colony‐stimulating factor; IL, interleukin; MI, myocardial infarction; and TNFα, tumor necrosis factor‐α.