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. 2024 May 10;109(7):1657–1683. doi: 10.1210/clinem/dgae250

Table 4.

Suggested tapering regimen depending on glucocorticoid dose

Patient's current daily prednisone equivalent dose Suggested prednisone decrements Time interval
>40 mg 5-10 mg decrease Every week
20-40 mg 5 mg decrease Every week
10-20 mg 2.5 mg decrease Every 1-4 weeks
5-10 mg 1 mg decrease Every 1-4 weeks
5 mg In absence of clinical symptoms or negative testing for adrenal insufficiency continue 1 mg decrease (if low dosage prednisolone preparations are not available, alternative: 20 mg hydrocortisone with 5 mg decrease) Every 4 weeks