Table 1.
Characteristics and Patient-Reported Outcomes by Fibromyalgia Criteria
| ICD-10 DIAGNOSIS |
PRO DIAGNOSIS |
||||||
|---|---|---|---|---|---|---|---|
| Total | Index Fibro | Total Fibro | Widespread-Heavy | CHOIR WPI | CHOIR WPI/SS | CHOIR WPI/PF | |
| Counts | 21,423 | 987 | 1850 | 2123 | 2036 | 1052 | 1999 |
| Age, years, mean ± SD | 60.19 ± 15.53 | 51.52 ± 13.36 | 53.39 ± 13.59 | 55.09 ± 13.98 | 53.43 ± 13.89 | 52.04 ± 13.18 | 53.45 ± 13.89 |
| Gender, male/total (%) | 40% | 7% | 8% | 29% | 27% | 26% | 27% |
| Racialized identity, n | 21,283 | 976 | 1836 | 2104 | 2018 | 1043 | 1981 |
| White, % yes | 83% | 77% | 78% | 81% | 81% | 80% | 81% |
| Black, % yes | 15% | 20% | 20% | 17% | 17% | 18% | 17% |
| Other, % yes | 2% | 3% | 2% | 2% | 2% | 2% | 2% |
| BMI, kg/m2, mean ± SD (n) | 30.61 ± 7.69 (n = 15,878) | 32.28 ± 9 (n = 693) | 31.97 ± 8.65 (n = 1309) | 31.81 ± 8.51 (n = 1473) | 31.94 ± 8.55 (n = 1418) | 32 ± 8.68 (n = 727) | 32.02 ± 8.58 (n = 1389) |
| Pain measures | |||||||
| Average Pain Intensity, mean ± SD | 6.49 ± 2.01 | 6.95 ± 1.75 | 6.83 ± 1.87 | 7.11 ± 1.78 | 7.27 ± 1.74 | 7.44 ± 1.67 | 7.28 ± 1.73 |
| Pain Interference, mean ± SD (n) | 66.36 ± 6.18 (n = 21,282) | 69.03 ± 5.59 (n = 977) | 68.4 ± 5.85 (n = 1835) | 69.33 ± 5.62 (n = 2097) | 70.16 ± 5.31 (n = 2019) | 71.45 ± 4.94 (n = 1049) | 70.32 ± 5.19 (n = 1982) |
| PainDetect total score, mean ± SD (n) | 16.5 ± 8.27 (n = 12,808) | 21.55 ± 7.2 (n = 637) | 20.98 ± 7.44 (n = 929) | 22.52 ± 7.26 (n = 1323) | 23.39 ± 7.18 (n = 1300) | 24.79 ± 6.68 (n = 598) | 23.55 ± 7.07 (n = 1275) |
| CHOIR body map regions selected, mean ± SD | 10.62 ± 11.03 | 27.6 ± 17.24 | 23.52 ± 16.78 | 34.2 ± 14.51 | 37.63 ± 12.13 | 38.5 ± 12.73 | 37.67 ± 12.13 |
| ACR body map regions selected, mean ± SD | 9.15 ± 9.16 | 22.98 ± 14.09 | 19.74 ± 13.75 | 28 ± 12.61 | 31.72 ± 9.75 | 32.33 ± 10.17 | 31.76 ± 9.75 |
| Overall health and function | |||||||
| Global mental health, mean ± SD (n) | 43.44 ± 9.43 (n = 18,520) | 37.33 ± 8.06 (n = 873) | 37.76 ± 8.36 (n = 1681) | 38.35 ± 8.94 (n = 1787) | 37.68 ± 8.71 (n = 1711) | 34.28 ± 7.35 | 37.53 ± 8.63 (n = 1681) |
| Global physical health, mean ± SD (n) | 35.6 ± 7.18 (n = 18,520) | 31.57 ± 5.67 (n = 873) | 32.22 ± 6.05 (n = 1681) | 31.19 ± 6.1 (n = 1787) | 30.51 ± 5.89 (n = 1711) | 28.96 ± 5.11 | 30.35 ± 5.72 (n = 1681) |
| Global health mean, mean ± SD (n) | 39.52 ± 7.41 (n = 18,520) | 34.45 ± 5.88 (n = 873) | 34.99 ± 6.28 (n = 1681) | 34.77 ± 6.49 (n = 1787) | 34.1 ± 6.26 (n = 1711) | 31.62 ± 5.13 | 33.94 ± 6.13 (n = 1681) |
| Physical Function, mean ± SD (n) | 35.28 ± 7.03 (n = 21,422) | 33.74 ± 5.82 (n = 987) | 33.9 ± 5.87 (n = 1850) | 32.51 ± 5.96 (n = 2123) | 31.97 ± 5.87 (n = 2036) | 30.79 ± 5.17 | 31.65 ± 5.42 |
| Sleep Disturbance, mean ± SD (n) | 59.68 ± 9.34 (n = 21,344) | 63.91 ± 8.29 (n = 980) | 63.03 ± 8.8 (n = 1842) | 64.01 ± 8.73 (n = 2107) | 65.06 ± 8.55 (n = 2025) | 68.02 ± 7.19 | 65.15 ± 8.55 (n = 1988) |
| Depression, mean ± SD (n) | 55.23 ± 10.43 (n = 21,344) | 60.76 ± 9.44 (n = 980) | 60.29 ± 9.45 (n = 1842) | 60.01 ± 10.1 (n = 2107) | 60.89 ± 9.99 (n = 2025) | 66.27 ± 6.56 | 61.04 ± 9.91 (n = 1988) |
| Anxiety, mean ± SD (n) | 56.27 ± 10.05 (n = 21,344) | 61.73 ± 8.95 (n = 980) | 61.29 ± 9.11 (n = 1842) | 60.79 ± 9.76 (n = 2107) | 61.76 ± 9.48 (n = 2025) | 66.76 ± 6.17 | 61.87 ± 9.45 (n = 1988) |
Abbreviations: PRO, Patient-Reported Outcome; Index Fibro, has ICD-10 diagnosis on index encounter; Total Fibro, has ICD-10 diagnosis associated with any encounter; Widespread-Heavy, hierarchical clustering subgroup based on pain body map alone; CHOIR WPI, proxy Widespread Pain Index derived from PROs; CHOIR WPI/SS, proxy combined WPI and Symptom Severity Score derived from PROs; CHOIR WPI/PF, proxy combined WPI and PROMIS Physical Function.