TABLE 1.

Characteristics of the asymptomatic study participants from the Munich & Tübingen DIAN cohorts at baseline α‐syn SAA assessments and numbers of consecutive α‐syn SAA assessments per participant.

	Asymptomatic mutation carriers (n = 26)	Mutation non‐carriers (n = 29)	P value
Age, years (SD)	35.2 (10.1)	34.6 (9.3)	0.82
Parental AAO, median years (interquartile range)	53 (47.0–56.3)	48 (40.5–52.5)	0.14
EYO (SD)	−16.6 (9.0)	N/A	N/A
Participants with 1/2/3/4 consecutive α‐syn SAA assessments, n	8/9/4/5	11/13/4/1	0.29

Abbreviations: AAO, age at onset; DIAN, Dominantly Inherited Alzheimer Network; EYO, estimated years from symptom onset; N/A, not applicable; SD, standard deviation; α‐syn SAA, α‐synuclein seed amplification assay.