Figure 3:
Auditory-nerve fibers (ANF) and spiral ganglion cells (SGC) are evidently decreased in ears ipsilateral to vestibular schwannoma (Figure 3A and 3B). ANF and SGC counts are affected differently by region of the cochlea (3C and 3D). Comparison to historical controls (Makary et al., 2011) suggests both ipsilateral and contralateral fibers are affected by the tumor, as the majority of contralateral SGC counts are below the average SGC counts based on age (Figure 3E). Tangent refers to the five tangents used to count ANFs in tangential sections, corresponding to tangential sections described in Figure 1, ascending in frequency along the x-axes. Segment refers to the four segments of the cochlea in which SGCs were counted (as in Merchant and Nadol, 2010), also ascending in frequency along the x-axes. Each patient is represented by a different color (consistent across panels; solid circles depict ipsilateral data and open circles depict contralateral data) and number (corresponding to patient numbers in table 1).