Table 2.

Our Hospital's Antimicrobial Stewardship Program Consensus Recommendations During Amphotericin B Shortage

Therapy for suspected or documented invasive mucormycosis Therapy for invasive fungal infection in patients with no alternative options Therapy for coccidioidomycosis during the first trimester of pregnancy Initial therapy for severe coccidioidomycosis Limit empiric usage to 72 h in high-riska patients (case-by-case basis)

^aHigh-risk indicates patients diagnosed with hematologic malignancy or recipients of hematopoietic stem cell transplant with worsening on anti-mold prophylaxis, and solid organ transplant recipients with recent treatment for rejection and worsening on anti-mold prophylaxis.