Supplementary Table 2.

Cancers with unspecified histology and topography codes referring to bile ducts identified in the 44 cohorts covered by Cancer Registry.

Region	Company or cohort name	Industrial activity	Gender	Cause of death	ICD-O		Incidence period	Age at death	Duration of exposure (years)	TSFE (years)
				ICD code*	Morphology code	Topography code
Piedmont	Amiantifera di Balangero	Chrysotile Mine	Male	156.9-Malignant neoplasm of biliary tract, part unspecified site	8000/3-Malignant tumor	C24.0-Extrahepatic bile duct	2010-2019	93	28	67
	Eternit	Asbestos Cement	Male	C22.1-Intrahepatic bile duct carcinoma	8000/3-Malignant tumor	C22.1-Intrahepatic bile duct	2010-2019	79	26	54
	Eternit	Asbestos Cement	Male	C23-Malignant neoplasm of gallbladder	8000/3-Malignant tumor	C24.9-Biliary tract, NOS	2010-2019	73	3	44
	SACA	Asbestos Cement	Male	C24.9-Malignant neoplasm of biliary tract, unspecified	8000/3-Malignant tumor	C24.0-Extrahepatic bile duct	2010-2019	82	0.33	57
Liguria	Cantieri Navali Genova	Shipyards	Male	155.1-Malignant neoplasm of intrahepatic bile ducts	8000/3-Malignant tumor	C24.0-Extrahepatic bile duct	2000-2009	83	17	44
	Cantieri Navali Genova	Shipyards	Male	156.9-Malignant neoplasm of biliary tract, part unspecified site	8000/3-Malignant tumor	C24.0-Extrahepatic bile duct	1990-1999	65	17	27
	Cantieri Navali Genova	Shipyards	Male	C24.9-Malignant neoplasm of biliary tract, unspecified	8000/3-Malignant tumor	C24.0-Extrahepatic bile duct	2010-2019	87	27	72
Veneto	Officine Grandi Riparazioni FS	Rolling stock maint	Male	155-Malignant neoplasm of liver and intrahepatic bile ducts	8000/3-Malignant tumor	C22.1-Intrahepatic bile duct	1990-1999	77	37	55
	Compagnia lavoratori Portuali	Harbour	Male	155.0-Malignant neoplasm of liver, primary	8000/3-Malignant tumor	C22.1-Intrahepatic bile duct	2000-2009	77	35	54
	Officine Grandi Riparazioni FS	Rolling stock maint	Male	155.1-Malignant neoplasm of intrahepatic bile ducts	8000/3-Malignant tumor	C22.1-Intrahepatic bile duct	2000-2009	58	2	35
	Fincantieri	Shipyard	Male	155.1-Malignant neoplasm of intrahepatic bile ducts	8000/3-Malignant tumor	C22.1-Intrahepatic bile duct	2000-2009	84	5	45
	Fincantieri	Shipyard	Male	156.1-Malignant neoplasm of extrahepatic bile ducts	8000/3-Malignant tumor	C24.0-Extrahepatic bile duct	2000-2009	77	25	51
	Fincantieri	Shipyard	Male	156.2-Malignant neoplasm of ampulla of Vater	8000/3-Malignant tumor	C24.9-Biliary tract, NOS	2000-2009	88	1	47
	Fincantieri	Shipyard	Male	156.9-Malignant neoplasm of biliary tract, part unspecified site	8000/3-Malignant tumor	C24.0-Extrahepatic bile duct	2000-2009	85	3	50
Emilia-Romagna	ICAR Eternit	Asbestos Cement	Male	156.9-Malignant neoplasm of biliary tract, part unspecified site	8000/3-Malignant tumor	C24.0-Extrahepatic bile duct	2000-2009	79	19	36
	Cemental/ICAR Eternit	Asbestos Cement	Male	156.9-Malignant neoplasm of biliary tract, part unspecified site	8000/3-Malignant tumor	C24.0-Extrahepatic bile duct	2000-2009	71	2	43
Tuscany	Cantieri Navali Apuania	Shipyard	Male	C22.1-Intrahepatic bile duct carcinoma	8000/3-Malignant tumor	C24.9-Biliary tract, NOS	2010-2019	81	3	34
	Compagnia lavoratori Portuali	Harbour	Male	C22.1-Intrahepatic bile duct carcinoma	8000/3-Malignant tumor	C24.9-Biliary tract, NOS	2010-2019	87	26	52
	Borma	Glassworks	Female	C22.9-Malignant neoplasm of liver, not specified as primary or secondary	8000/3-Malignant tumor	C22.1-Intrahepatic bile duct	2010-2019	93	5	74
	Borma	Glassworks	Male	C24.9-Malignant neoplasm of biliary tract, unspecified	8000/3-Malignant tumor	C24.0-Extrahepatic bile duct	2010-2019	76	22	43
	Fervet	Rolling stock maint and cons	Male	C24.9-Malignant neoplasm of biliary tract, unspecified	8000/3-Malignant tumor	C24.9-Biliary tract, NOS	2010-2019	71	0.01	49

*ICD-8 codes: 155 and 156; ICD-9 codes: 155 and 156; and ICD-10 codes: C22, C23 and C24.

Abbreviations: Cons, Construction; ICD-O, International Classification of Diseases for Oncology; Maint, Maintenance; TSFE, time since first exposure.