Table 2. MIC₅₀ (μM) Values of the Linezolid Bioisosteres against Drug Resistant Mtb Clinical Isolates^a.

^ainhA+: Low-grade isoniazid resistant clinical isolate with mutation in the promoter region. katG+: High-grade isoniazid resistant clinical isolate with S315T mutation. rpoB+: High-grade rifampicin resistant clinical isolate with S531L mutation. MDR: High-level isoniazid, rifampicin, ethambutol, and pyrazinamide resistance, with mutations in inhA, katG, rpoB (H526D mutation detected), and eis genes. No Mutation: Mtb clinical isolate with no mutation.