Table 3.
Clinicopathologic characteristics of 564 patients in CTR<0.7, 0.7≤CTR<1 and CTR=1 groups
| Variable | CTR<0.7 (N = 3691) | 0.7≤CTR<1 (N = 781) | CTR=1 (N = 1171) | p-value2 |
|---|---|---|---|---|
| Sex | <0.001 | |||
| Male | 122 (33%) | 32 (41%) | 66 (56%) | |
| Female | 247 (67%) | 46 (59%) | 51 (44%) | |
| Age | <0.001 | |||
| >56 | 159 (43%) | 36 (46%) | 75 (64%) | |
| ≤56 | 210 (57%) | 42 (54%) | 42 (36%) | |
| Type | <0.001 | |||
| AAH/AIS/MIA | 265 (72%) | 10 (13%) | 1 (0.9%) | |
| IAC | 104 (28%) | 68 (87%) | 116 (99%) | |
| Tumor size | 12.0 (9.5, 15.6) | 14.9 (12.4, 17.5) | 16.2 (11.9, 18.4) | <0.001 |
| Solid size | 4.0 (0.0, 6.4) | 12.1 (10.3, 14.2) | 16.2 (11.9, 18.4) | <0.001 |
| Surgery approach | <0.001 | |||
| Lobar resection | 130 (35%) | 52 (67%) | 84 (72%) | |
| Sublobar resection | 239 (65%) | 26 (33%) | 33 (28%) | |
| Pathology grade | ||||
| AAH/AIS/MIA/Well differentiated | 306 (83%) | 12 (15%) | 1 (0.9%) | |
| Moderately differentiated | 61 (17%) | 60 (77%) | 91 (78%) | |
| Poorly differentiated | 2 (0.5%) | 6 (7.7%) | 25 (21%) |
1n (%); Median (IQR). 2Pearson’s Chi-squared test; Kruskal-Wallis rank sum test; Fisher’s exact test. AAH: atypical adenomatous hyperplasia; AIS: adenocarcinoma in situ; CTR: consolidation tumor ratio; IAC: invasive adenocarcinoma; MIA: minimally invasive adenocarcinoma