Table 1.

Baseline characteristics of the study population, instillation treatments and outcome domains

Bladder cancer morphology	Studies	POPULATION							INSTILLATION TREATMENT (S-single; I- induction; M-maintainance)	Number of outcomes domains (n/10)
		pTa		pT1		CIS as authors have reported
		low grade	high grade	low grade	high grade	primary cis	secondary cis	concomitant cis
CIS+/- PAPILLARY	Lamm 2000	x	x	x	x	x		x	M	7
	Palou 2001		G3		G3	x		x	M	6
	Au 2001	x	x	x	x	x		x	I	2
	Sekine 2001	x	x	x	x	x	x	x	I	5
	Martinez-Pinneiro 2002		G2G3	G1	G2G3	x		x	I	7
	Di Stasi 2003			x	x	x		x	M	7
	Kaasinen 2003	x	x	x	x	x	x	x	M	5
	Martinez-Pinneiro 2005		G3		G3	x		x	I	4
	de Reijke 2005	x	x	x	x	x	x	x	M	5
	Di Stasi 2006				G2G3			x	M	6
	Gårdmark 2007	x	x	x	x	x		x	M	4
	Cai 2008		G2G3	G2				x	M	4
	Neple 2010	x	x	x	x	x		x	M	2
	Porena 2010		G3		G3	x		x	M	3
	Koga 2010		x	x	x			x	M	5
	Gülpınar 2012	x	x	x	x	x		x	I	4
	Järvinen 2012					x	x	x	M	5
	Sengiku 2013	x	x	x	x	x	x	x	I	3
	Inamoto 2013	x	x	x	x	x	x	x	I	4
	Rentsch 2014	x	x	x	x			x	I	5
	Hemdan 2014				G2G3			x	M	4
	Martinez-Pineiro 2015	G1G2 + cis	G3	G1G2 + cis	G3			x	I vs M	5
	Solsona 2015	G1 + cis	G2G3	G1	G2G3	x		x	I	5
	Arends 2016	x	x	x	x	x	x	x	M	4
	Nakai 2016	x	x	x	x	x		x	I vs M	5
PAPILLARY	Kaasinen 2000	G1G2		G1G2					M	2
	Bilen 2000				x				I	4
	Van der Meijden 2001	x	x	x	x				M	4
	Nomata 2002	G1G2		G1G2					M	2
	Okamura 2002	x	x	x	x				S	3
	Rajala 2002	x	x	x	x				S	1
	Kuroda 2004	G1G2		G1G2					M	4
	Koga 2004	x	x	x	x				I vs M	2
	Mitsumori 2004	x	x	x	x				I	2
	Cheng 2005	x	x	x	x				M	5
	Vijjan 2006	x	x	x	x				I	5
	Hinotsu 2006	x	x	x	x				I vs M	3
	Barghi 2006	G1G2		G1					S	3
	Ojea 2007		G2	G1G2					M	4
	El-Ghobashy 2007	G1G2		G1G2					S	4
	Agrawal 2007	x	x	x	x				M	2
	Friedrich 2007	x	x	x	x				M	2
	Hendricksen 2008	x	x	x	x				M	3
	Berrum-Svennung 2008	G1G2		G1G2					S	3
	Isbarn 2008	x	x	x	x				I vs M	2
	Böhle 2009	x	x	x	x				S	4
	Gudjonsson 2009	G1G2		G1G2					S	1
	Järvinen 2009	x	x	x	x				M	5
	Seretta 2010	G1G2		G1G2					I vs M	3
	Sylvester 2010	x	x	x	x				M	6
	De Nunzio 2011	G1G2							S	4
	Di Stasi 2011	x	x	x	x				S	5
	Hinotsu 2011	x	x	x	x				I vs M	4
	Oddens 2013	x	x	x	x				M	6
	Huang 2015	x	x	x	x				M	4
	Onishi 2017	G1G2		G1G2					S	3
	Bijalwan 2017	x	x	x	x				S	3