Table 2.
Multivariable Models for QOL by Health State
| Model | Outcome | Variable | Estimate | p-value | |
| 1 | EORTC Summary Score | Health State (Ref: Non-recurrent NMIBC) | Recurrent NMIBC | –1.3 | 0.25 |
| MIBC | –4.1 | 0.002 | |||
| Metastatic | –6.5 | 0.002 | |||
| Treatment (Ref: Conservative) | Cystectomy | 0.29 | 0.8825 | ||
| Time Since Treatment (Ref: < 1 year) | > 1 year | 3 | 0.0016 | ||
| 2 | EORTC Emotional Functioning | Health State (Ref: Non-recurrent NMIBC) | Recurrent NMIBC | –1.9 | 0.31 |
| MIBC | –4.7 | 0.04 | |||
| Metastatic | –6.8 | 0.048 | |||
| Treatment (Ref: Conservative) | Cystectomy | 4.3 | 0.03 | ||
| Time Since Treatment (Ref: < 1 year) | > 1 year | 4.1 | 0.01 | ||
| 3 | EORTC Physical Functioning | Health State (Ref: Non-recurrent NMIBC) | Recurrent NMIBC | –1.5 | 0.48 |
| MIBC | –4.1 | 0.11 | |||
| Metastatic | –8.1 | 0.03 | |||
| Treatment (Ref: Conservative) | Cystectomy | –1.5 | 0.49 | ||
| Time Since Treatment (Ref: < 1 year) | > 1 year | 4.6 | 0.009 | ||
| 4 | BCI Urinary Summary Score | Health State (Ref: Non-recurrent NMIBC) | Recurrent NMIBC | –0.9 | 0.55 |
| MIBC | –3.2 | 0.07 | |||
| Metastatic | –5.3 | 0.047 | |||
| Treatment (Ref: Conservative) | Cystectomy | –5.1 | 0.008 | ||
| Time Since Treatment (Ref: < 1 year) | > 1 year | 2.9 | 0.01 | ||
| 5 | BCI Sexual Summary Score | Health State (Ref: Non-recurrent NMIBC) | Recurrent NMIBC | –0.6 | 0.79 |
| MIBC | –2.8 | 0.33 | |||
| Metastatic | –10.9 | 0.01 | |||
| Treatment (Ref: Conservative) | Cystectomy | –11.7 | < 0.001 | ||
| Time Since Treatment (Ref: < 1 year) | > 1 year | 4 | 0.047 | ||
| 6 | BCI Bowel Summary Score | Health State (Ref: Non-recurrent NMIBC) | Recurrent NMIBC | –1.5 | 0.16 |
| MIBC | –3.3 | 0.01 | |||
| Metastatic | –2.5 | 0.19 | |||
| Treatment (Ref: Conservative) | Cystectomy | –0.4 | 0.7 | ||
| Time Since Treatment (Ref: < 1 year) | > 1 year | 1 | 0.29 |
*Model adjusted for additional covariates: age, gender, partner status, insurance, income, education, and time since treatment.