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. 2024 Jun 14;13(1):2367777. doi: 10.1080/2162402X.2024.2367777

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© 2024 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 1. — CD27/28-CD57+ T cells and their CD27/28+ counterparts were isolated from the peripheral blood and tumor tissue of HNSCC patients. (a) Flow cytometry gating strategy used for CD8+ and CD4+ subsets. (b) KLRG1 expression among T cell subsets in the peripheral blood (left) and tumor infiltrating lymphocytes (TIL, right). MFI, mean fluorescence intensity. (c) TIGIT expression among T cell subsets in the peripheral blood (left) and TIL (right). (d) Correlation (Pearson correlation coefficient, squared) between percent of CD27/28-CD57+ T cells in the peripheral blood versus TIL for CD8+ subsets (left) and CD4+ subsets (right). Data in B and C represent mean ± one SD. **p < .01, ***p < .001, ****p < .0001 by two-way ANOVA with post hoc Tukey analyses.