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. 2023 Nov 6;5:ojad100. doi: 10.1093/asjof/ojad100

Table 4.

Efficacy of Radiofrequency Microneedling

Study Technique Aesthetic target Summary/outcomes
Kim et al33 Fractional radiofrequency microneedling Periorbital wrinkles Significant reduction in wrinkles and improvement in satisfaction
Lee et al34 Fractional radiofrequency microneedling Periorbital wrinkles All patients were satisfied with treatment and most received clinical and photographic assessment improvement
Kwon et al35 Monopolar radiofrequency microneedling Periorbital wrinkles Long microneedling is preferable to short microneedling and results in significantly improved photographic assessments
Jeon et al36 Fractional radiofrequency microneedling Periorbital wrinkles Long-term results for improvement of periorbital wrinkles are superior in microneedling in comparison to botulinum toxin
Gold et al37 Fractional radiofrequency microneedling Mid- and lower face laxity and wrinkles Significant wrinkle reduction, skin tightening, and lifting of the mid- and lower face resulted from the treatment
Alexiades et al38 Bipolar fractional radiofrequency microneedling Face and neck rhytides and laxity Temperature-controlled bipolar radiofrequency results in high levels of patient satisfaction, and significant reduction in wrinkles and skin laxity
Zhang et al39 Fractional radiofrequency microneedling Facial photoaging There were high levels of patient satisfaction and significant improvements in 2 measures of facial photoaging (rhytides, skin tightening, complexion)
Liu et al40 Fractional radiofrequency microneedling Rhytids and facial laxity 3-Dimensional imaging revealed improvement in roughness parameters as an indication of treatment efficacy in photoaging
Seo et al41 Fractional radiofrequency microneedling Skin rejuvenation Objective measures (skin hydration, roughness, histological findings dermal thickness, collagen content) and subjective measures (patient satisfaction) all improved after treatment
Alexiades et al42 Fractional radiofrequency microneedling Facial and neck rhytides Treatment had a 100% response rate, identifying an optimal dermal temperature of 67°C with a duration of 3 to 4 s
Lu et al43 Fractional radiofrequency microneedling Nasolabial and infraorbital rhytides Treatments targeting the deep dermal layer were more effective than superficial, and nasolabial folds responded to treatment more than infraorbital rhytids