TABLE 3.

Summary of CD4 and CD8 expression on human thymocytes derived from SCID-hu thymus/liver grafts 3 and 6 weeks after infection with HIV-1 ACH142-8G9, ACH142-32D2, and ACH142-^*E11^a

Mouse	Virus	Cell distribution
		3 wk				6 wk
		% CD4+	% CD8+	% CD4+ CD8+	CD4+/CD8+	% CD4+	% CD8+	% CD4+ CD8+	CD4+/CD8+
38-5	Mock	8	4	87	2.0	15	6	78	2.5
38-26	Mock	10	5	85	2.0	10	6	81	1.7
47-14	Mock	16	6	78	2.7	13	4	83	3.3
38-6	8G9	12	6	81	2.0	18	8	74	2.3
47-16	8G9	9	4	86	2.3	9	6	85	1.5
47-18	8G9	19	8	73	2.4	18	7	74	2.6
49-5	8G9	13	4	83	3.3	12	5	83	2.4
49-30	8G9	16	5	78	3.2	14	7	78	2.0
38-8	32D2	17	7	73	2.4	19	12	60	1.6
47-11	32D2	27	11	60	2.5	6	3	89	2.0
47-12	32D2	13	4	83	3.3	17	7	75	2.4
47-19	32D2	19	10	69	1.9	12	6	82	2.0
49-11	32D2	13	3	83	4.3	14	5	80	2.8
38-12	*E11	20	9	71	2.2	23	15	59	1.5
38-14	*E11	12	5	83	2.4	13	12	73	1.1
38-18	*E11	23	10	68	2.3	18	15	63	1.2
38-20	*E11	19	9	71	2.1	33	34	23	1.0
30-42	*E11	33	51	13	0.6	21	48	28	0.4
49-13	*E11	13	5	81	2.6	16	6	77	2.7
49-17	*E11	14	5	79	2.8	14	16	67	0.9
46-13 +/Δ32	*E11					9	5	85	1.8
46-15 +/Δ32	*E11					8	5	86	1.6
46-27 +/Δ32	*E11					12	6	81	2.0
46-29 +/Δ32	*E11					8	4	88	2.0
38-25	NL4-3	18	14	66	1.3	22	44	9	0.5
30-24	NL4-3	11	5	83	2.2	27	54	3	0.5
49-28	NL4-3	13	7	79	1.9	31	34	20	0.9

^aThymus/liver implants from several donors were infected with 1,000 TCID₅₀ of HIV-1 ACH142-8G9, ACH142-32D2, ACH142-*E11, or NL4-3. Implants were from CCR5 +/+ homozygous donors except for implant 46, which was derived from a CCR5 +/Δ32 heterozygous donor. The CCR5 +/Δ32 grafts were biopsied only at 6 weeks postinfection.