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. 2023 Jul 31;3:1230084. doi: 10.3389/fopht.2023.1230084

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Copyright © 2023 Songco-Aguas, Grimes and Rieke

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Interference between rod- and cone-generated signals in human perception. (A) General setup for human perceptual experiments to probe rod-cone signal integration. (B, C) Mean flicker thresholds for rod- (B, blue) and cone- (C, red) isolating stimuli across a range of temporal frequencies. Purple data points reflect thresholds obtained from trial when both rod and cone stimuli flickered simultaneously. (D, E) Introducing phase shifts between rod and cone flicker (stimuli) shift interactions from destructive to constructive (e.g. 8 Hz; D) and vice-versa (e.g. 4 Hz; E). Data is pooled from 2 authors and 3 naive subjects.