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. Author manuscript; available in PMC: 2024 Jun 17.
Published in final edited form as: Drug Discov Today. 2022 Apr 27;27(7):2008–2014. doi: 10.1016/j.drudis.2022.04.021

Figure 5. Examples of recent antipsychotic drug SOSA efforts. (A) Fluphenazine and analog CWHM-974 with improved antifungal potency and reduced affinity for dopamine and serotonin receptors. (B) Haloperidol and analog B10 with improved antifungal potency and dopamine selectivity. (C) Sertraline and analog D16 with improved antifungal potency.

Figure 5.

Chemical differences are colored blue.