Table 3.

Unadjusted and adjusted odds ratios of GBS EOS infection incidence by treatment type with pooled logistic regression.

Unadjusted odds ratios of GBS EOS infection incidence by treatment type
Treatment group	Unadjusted OR (95% CI)	p-value
First-line	(reference)	-
Second-line	3.21 (2.13 – 4.82)	<.001
No antibiotics	3.27 (2.36 – 4.54)	<.001
Adjusted odds ratios of GBS EOS infection incidence by treatment type with pooled multivariable logistic regression
Treatment group	Adjusted odds ratio, aOR (95% CI)	p-value
First-line	(reference)	-
Second-line	4.12 (2.66 – 6.38)	<.001
No antibiotics	3.80 (2.66 – 5.44)	<.001
Second-line	(reference)	-
First-line	0.24 (0.16 – 0.38)	<.001
No antibiotics	0.92 (0.64 – 1.33)	.66
Covariates
Maternal age	0.96 (0.94 – 0.99)	.005
Race
White	(reference)	-
Black	1.01 (0.70 – 1.46)	.96
Hispanic	0.72 (0.48 – 1.09)	.12
Other	1.62 (0.98 – 2.70)	.06
Use of instrumentation	0.65 (0.30 – 1.40)	.27
Prolonged rupture of membranes	1.05 (0.58 – 1.89)	.88
Gestational age	1.19 (1.05 – 1.35)	.007
Birth weight	0.92 (0.71 – 1.20)	.54
Male gender	0.72 (0.54 – 0.97)	.029
Vaginal birth	1.33 (0.98 – 1.81)	.07
5-minute APGAR	0.80 (0.75 – 0.86)	<.001

GBS, Group B Streptococcus; EOS, Early-Onset Sepsis. The aOR for vaginal birth in compared to the reference group of Caesarean section births.