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. Author manuscript; available in PMC: 2024 Jun 17.
Published in final edited form as: Am J Obstet Gynecol. 2023 Oct 25;230(6):673.e1–673.e8. doi: 10.1016/j.ajog.2023.10.035

Table 4.

Outcomes of GBS EOS episodes based on peripartum antibiotic received for full term neonates with GBS positive mothers.

First-line antibiotics
(n = 51)
Second-line antibiotics
(n = 42)
No antibiotics
(n = 122)
p-value
Postnatal age at positive GBS culture, median [IQR], days 0 [0, 0] 0 [0, 0] 0 [0, 1] .004
Pressor use in first week of life 5 (9.8) 4 (9.5) 14 (11.5) .91
Invasive ventilation in first week of life 9 (17.6) 9 (21.4) 24 (19.7) .90
Days of invasive ventilation, median [IQR] 0 [0, 0] 0 (0, 0) 0 [0, 0] .94
Percent days with invasive ventilation, median [IQR] 0 [0, 0] 0 (0, 0) 0 [0, 0] .87
Days on supplemental oxygen, median [IQR] 1 [0, 3] 0 [0, 2] 1 [0, 3] .36
Percent days with supplemental oxygen, median [IQR] 9 [0, 26] 0 [0, 18] 8 [0, 20] .37
Length of stay (days), median [IQR] 11 [10, 12] 11.5 [11, 14] 12 [11, 15] 0.06

Data are presented as n (%) unless otherwise specified.

GBS, Group B Streptococcus; EOS, Early-Onset Sepsis.

Chi square and Kruskal-Wallis tests were used to assess for differences across groups by type of antibiotic received for each variable.