TABLE 1.

RT activities of selectively mutated RSV RTs^a

Enzyme	% of wild-type activityb
αD181NPol	7.5 ± 2.5
αβD181N	42 ± 10
αD181NβD181N	1.5 ± 0.5
αD505NPol	34 ± 6
αβD505N	74 ± 15
αD505NβD505N	32 ± 7

^aRNA-dependent DNA polymerase activity was quantitated on a poly(rA) · oligo(dT)_12–18 substrate as described previously (37). The activities of αPol and αβ were set to 100%. 

^bValues are means ± standard deviations.