Aydin 2013.

Methods	Single centre, parallel. Randomisation was performed with the use of a computer generated random numbers, upon enrolment an opaque envelope was opened Follow up until clinical pregnancy. ITT was performed Duration: from September 2011 to January 2013
Participants	220 women, 220 first cycles Inclusion criteria: normal hysterosalpingography, normal hormone essay, semen analysis total progressive motile sperm count > 5 million/ml with > 4% morphology after sperm preparation Exclusion criteria: women with endocrinologic disorders, women with any history of surgery on the reproductive system, women < 20 years and > 35 years, women with expected to be poor responders due to day 3 baseline ultrasonography and or FSH > 10 mIU/ml, estradiol > 40 pg/ml and an antral follicle count (AFC < 6), women who had previously smoked, with advanced male factor infertility (referred for IVF) Mean age of women: 34 to 36 hrs after hCG group: 30.6 ± 3.4 IUI with hCG: 30.7 ± 3.3 Duration of subfertility: 4.9 ± 4.9 years 34 to 36 hrs after hCG group, 5.2 ± 4.7 years, IUI with hCG group Type of subfertility: unexplained, male factor
Interventions	75 to 112.5 IU r‐FSH from cycle day 3, with low dose step up. Ovulation triggering 250 µg r‐hCG Type of semen: partner Insemination procedure: two‐layer density gradient separation technique, single IUI
Outcomes	Outcome pregnancy rate per couple: 10/106 (9.4%) 34 to 36 hrs after hCG, 12/98 (12.2%) IUI with hCG group Secondary outcome measures: not stated Costs: not stated Pregnancy diagnosed: presence of an embryo with cardiac activity on ultrasound
Notes	Setting: Eskisehir Osmangazi University, Center for Reproductive Health, Eskisehir, Turkey Long duration of subfertility No funding stated