Table 2.
Changes in predictive accuracy for 30-day mortality and non-home discharge with addition of frailty indices to base prediction model
| Base | Base + RAI | Base + mFI-5 | |
|---|---|---|---|
| 30-day Mortality | |||
| AUC | 0.77 (0.76, 0.79) | 0.78 (0.76, 0.79) | 0.77 (0.76, 0.79) |
| ICI | 0.01 (0.00, 0.02) | 0.01 (0.00, 0.02) | 0.01 (0.00, 0.02) |
| Reclassification | |||
| Events (%) | −40 | −10 | |
| Non-events (%) | 57 | 21 | |
| NRI | 0.17 (0.06, 0.35) | 0.09 (−0.09, 0.19) | |
| TPR (%) | 74 | 75 | 74 |
| FPR (%) | 35 | 34 | 35 |
| TNR (%) | 65 | 66 | 65 |
| FNR (%) | 26 | 25 | 26 |
| Non-home Discharge | |||
| AUC | 0.74 (0.71, 0.77) | 0.75 (0.72, 0.78) | 0.75 (0.72, 0.77) |
| ICI | 0.02 (0.01, 0.04) | 0.03 (0.01, 0.05) | 0.02 (0.01, 0.04) |
| Reclassification | |||
| Events (%) | −32 | −12 | |
| Non-events (%) | 56 | 31 | |
| NRI | 0.24 (0.10, 0.36) | 0.18 (−0.02, 0.31) | |
| TPR (%) | 45 | 45 | 46 |
| FPR (%) | 12 | 12 | 12 |
| TNR (%) | 88 | 88 | 88 |
| FNR (%) | 55 | 55 | 54 |
Abbreviations: RAI = Risk Analysis Index; mFI-5 = 5-factor Modified Frailty Index; AUC = area under the receiver operating curve; ICI = integrated calibration index; NRI = continuous net reclassification index; TPR = true positive rate; FPR = false positive rate; TNR = true negative rate; FNR = false negative rate.