Table A.2.
Changes in predictive accuracy for 30-day mortality and non-home discharge with addition of frailty indices as binary variables to base prediction model
| Base | Base + RAI | Base + mFI-5 | |
|---|---|---|---|
| 30-day Mortality | |||
| AUC | 0.77 (0.76, 0.79) | 0.77 (0.76, 0.79) | 0.77 (0.76, 0.79) |
| ICI | 0.01 (0.00, 0.02) | 0.01 (0.00, 0.02) | 0.01 (0.00, 0.02) |
| Reclassification | |||
| Events (%) | −38 | −33 | |
| Non-events (%) | 56 | 44 | |
| NRI | 0.18 (−0.14, 0.24) | 0.10 (−0.09, 0.17) | |
| TPR (%) | 74 | 74 | 74 |
| FPR (%) | 35 | 34 | 34 |
| TNR (%) | 65 | 66 | 66 |
| FNR (%) | 26 | 26 | 26 |
| Non-home Discharge | |||
| AUC | 0.74 (0.71, 0.77) | 0.75 (0.72, 0.78) | 0.75 (0.72, 0.78) |
| ICI | 0.02 (0.01, 0.04) | 0.03 (0.01, 0.04) | 0.02 (0.01, 0.04) |
| Reclassification | |||
| Events (%) | −37 | −28 | |
| Non-events (%) | 68 | 58 | |
| NRI | 0.30 (0.18, 0.41) | 0.29 (0.09, 0.42) | |
| TPR (%) | 45 | 46 | 46 |
| FPR (%) | 12 | 13 | 13 |
| TNR (%) | 88 | 87 | 87 |
| FNR (%) | 55 | 54 | 54 |
Abbreviations: RAI = Risk Analysis Index; mFI-5 = 5-factor Modified Frailty Index; AUC = area under the receiver operating curve; ICI = integrated calibration index; NRI = continuous net reclassification index; TPR = true positive rate; FPR = false positive rate; TNR = true negative rate; FNR = false negative rate.