Fig. 7. H3R26C expressing MPCs follow an aberrant differentiation trajectory compared to MPCs expressing H3WT.

A Trajectory analysis of the same single cell RNA-seq data from Fig. 6 demonstrating a differentiation path (gray line) and distance in pseudotime (gradient scale shown). B Individual samples (defined by genotype and treatment) were projected onto the UMAP with pseudotime indicated by the gradient scale shown.