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. 2024 Jun 17;14:13968. doi: 10.1038/s41598-024-64495-6

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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STING facilitates glomerulonephritis in pristane-induced lupus. The tissues (kidney and lung) were sectioned and stained with Hematoxylin and eosin stain (H&E). (A) The section of kidneys from pristane-induced mice showed glomerulonephritis (scale bar 100 µm). (B) Serum creatinine (mg/dL). The kidney histopathology was graded for (C) glomerulonephritis (glomerular score) and (D) interstitial nephritis (interstitial score). Data are shown as mean ± SD. p-values were indicated *p < 0.05, **p < 0.01, and ***p < 0.001. (N = 16–18 mice/group).