Table 1.
Association between TRPV1+ nerve infiltration and clinical grade, T staging, and lymph node metastasis of OSCC patients
| Variables | TRPV1+ nerve negative/number of cases (%) | TRPV1+ nerve positive/number of cases (%) | P-value |
|---|---|---|---|
| Clinical grade | 0.022 | ||
| Grade1 | 9 (69%) | 4 (31%) | |
| Grade2 | 25 (71%) | 10 (29%) | |
| Grade3 | 18 (49%) | 19 (51%) | |
| Grade4 | 13 (45%) | 16 (55%) | |
| T stage | 0.105 | ||
| T1 | 12 (60%) | 8 (40%) | |
| T2 | 35 (63%) | 21 (38%) | |
| T3 | 14 (70%) | 6 (30%) | |
| T4 | 6 (32%) | 13 (68%) | |
| Lymph node metastasis | 0.023 | ||
| Negative | 43 (68%) | 20 (32%) | |
| Positive | 24 (46%) | 28 (54%) |
The association between clinical staging or T staging and TRPV1+ nerve infiltration was examined using the Cochran-Armitage trend test, while the relationship between lymph node metastasis and TRPV1+ nerve infiltration was assessed using Fisher’s exact test