FIG. 2.

Comparison of TR339 virus titers from multiple tissues at 72 h p.i. 129 Sv/Ev IFN-α/βR^+/+ mice (open bars), IFN-α/βR^+/− heterozygous mice (hatched bars), and IFN-α/βR^−/− mice (solid bars) were inoculated, and tissues were harvested as described in Fig. 1. The values represent the geometric mean virus titer (log₁₀ PFU/ml or g) for two (IFN-α/βR^+/−) or three (IFN-α/βR^−/− and 129 Sv/Ev) mice. Datum points are shown ± the SD, where n = 3. A 0.5 log₁₀ PFU/ml bar denotes a value below the limit of detection, i.e., <1.88 log₁₀ PFU/g for brain, <2.40 log₁₀ PFU/ml for serum, and <2.18 log₁₀ PFU/g for all other tissues.