FIG. 9.

Possible models for interdigitation of replication complexes with sites of virion assembly. (A) Replication complexes throughout the cytoplasm (black) move along cytoskeletal pathways to sites juxtaposed to IC-Golgi membranes. (B) RNA-nucleocapsids move from replication complexes (dark grey) via separate transport complexes (black). (C) Only amplified or newly formed replication complexes (black) directly adjacent to the IC-Golgi membranes interact with sites of assembly. The model is not intended to describe the source of membranes for replication complexes.