Table 4.

Estimates of mean outcomes by treatment group over 12-month treatment period for all patients (based on available data)

Item	Craniotomy (N=126)	DC (N=122)	P value*
Baseline EQ-5D-5L score, mean±SD	0.260±0.353 (n=87)	0.302±0.366 (n=91)	0.441
6-month EQ-5D-5L score, mean±SD	0.427±0.392 (n=102)	0.370±0.393 (n=94)	0.311
6-month change in EQ-5D-5L score, mean±SD	0.184±0.345 (n=74)	0.073±0.319 (n=71)	0.046
12-month EQ-5D-5L score, mean±SD	0.471±0.402 (n=111)	0.336±0.414 (n=103)	0.016
12-month change in EQ-5D-5L score, mean±SD	0.218±0.367 (n=79)	0.073±0.361 (n=78)	0.013
Total QALY score, mean±SD	0.351±0.335 (n=68)	0.338±0.366 (n=64)	0.830
12-month GOSE score, % favourable†	47.9 (n=121)	37.4 (n=115)	0.102

*For the mean difference between groups.

†Favourable for the GOSE score was defined as upper severe disability or better.

DC, decompressive craniectomy; EQ-5D-5L, EuroQoL 5-Dimension 5-Level; GOSE, Extended Glasgow Outcome Scale; n, number for whom data were available; N, number allocated to that trial arm; QALY, quality-adjusted life-year; SD, standard deviation.