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. 2024 Jun 7;28(2):362. doi: 10.3892/ol.2024.14495

Table IV.

Kaplan-Meier estimates of time-to-event outcomes.

LPC

Time-to-event outcome Non-high-risk High-risk LAPC Overall
PSA progression-free survivala
  n 361 208 106 675
  Median (95% CI), months n.a. n.a. n.a. n.a.
  1-year rate (95% CI), % 98.9 97.1 100.0 98.5 (97.6–99.4)
  5-year rate (95% CI), % 87.4 78.7 79.9 82.9 (77.3–100.0)
Metastasis-free survivalb
  n 366 233 110 709
  Median (95% CI), months n.a. n.a. n.a. n.a.
  1-year rate (95% CI), % 98.9 98.3 100.0 98.9 (98.1–99.7)
  5-year rate (95% CI), % 91.8 78.5 91.7 87.5 (82.6–92.7)
Disease-free survivala
  n 361 208 106 675
  Median (95% CI), months n.a. n.a. n.a. n.a.
  1-year rate (95% CI), % 99.2 98.1 100.0 98.9% (98.2–99.7)
  5-year rate (95% CI), % 88.4 79.9 79.1 83.7 (78.0–89.8)
Progression-free survivalc
  n 22 39 10 71
  Median (95% CI), months 32.9 (27.1–46.0) 29.5 (24.4–44.5) 29.1 (26.3–41.8) 29.9 (26.5–41.0)
  1-year rate (95% CI), % 90.5 86.5 100.0 89.7 (92.7–97.2)
  5-year rate (95% CI), % 0.0 0.0 0.0 0.0
Overall survivald
  n 433 244 113 790
  Median (95% CI), months n.a. n.a. n.a. n.a.
  1-year rate (95% CI), % 100.0 99.2 100.0 99.8 (99.4–100)
  5-year rate (95% CI), % 96.8 88.8 87.9 92.9 (90.2–95.7)
a

In patients treated with curative intent (n=675),

b

in patients treated with curative or palliative intent (n=709),

c

in patients treated with palliative intent (n=71),

d

in all patients (n=790). LPC, localised prostate cancer; LAPC, locally advanced prostate cancer; CI, confidence interval; n.a., median not achieved.