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. 2024 Jun 18;14(27):19512–19527. doi: 10.1039/d4ra02738h

Binding constant data (Kb, Ksv) along with % hypochromism (% H) obtained from the interaction study of the compounds with ctDNA and tRNA.

Compd λ max Absorption spectroscopy Emission spectroscopy (at λem = 580 nm)
(Kb), × 106 % H* (Ksv),×104 % H
ctDNA tRNA ctDNA tRNA ctDNA tRNA ctDNA tRNA
HL 314 1.10 1.36 8.35 7.20 0.34 1.19 32.4 26.1
(C1) 320 4.71 10.3 12.7 8.67 4.91 7.52 55.4 61.5
(C2) 329 2.58 8.96 10.4 7.60 1.42 4.51 54.2 48.8
(C3) 319 1.22 1.51 6.81 6.66 0.52 1.6 50.1 26.9