Table 1.
Characteristics of the 38 subjects in the study population
| Characteristics | Population |
Healthy control |
Enteric hyperoxaluria |
Primary hyperoxaluria |
CKS former |
P-value∗ |
|---|---|---|---|---|---|---|
|
n |
13 |
5 |
8 |
12 |
||
| Age | 39.1 (11.8) | 55.6 (14.5) | 33.0 (13.6) | 47.5 (13.8) | 0.017 | |
| Sex | Female | 7 (53.8%) | 4 (80%) | 6 (75%) | 4 (33.3%) | 0.222 |
| Male | 6 (46.2%) | 1 (20%) | 2 (25%) | 8 (66.7%) | ||
| Ethnicity | Hispanic or Latino | 2 (15.4%) | 0 (0%) | 0 (0%) | 1 (8.3%) | 0.852 |
| not Hispanic or Latino | 11 (84.6%) | 5 (100%) | 8 (100%) | 11 (91.7%) | ||
| Race | American Indian | 0 (0%) | 0 (0%) | 1 (12.5%) | 0 (0%) | 0.834 |
| White | 11 (84.6%) | 5 (100%) | 6 (75.0%) | 10 (83.3%) | ||
| Other | 2 (15.4%) | 0 (0%) | 1 (12.5%) | 2 (16.7%) | ||
| Body Measures | Height (cm) | 166 (10.5) | 167 (7.82) | 170 (4.60) | 174 (8.62) | 0.165 |
| Weight (kg) | 70.4 (13.7) | 99.4 (19.6) | 72.3 (8.40) | 83.5 (21.2) | 0.016 | |
| BMI | 25.2 (3.43) | 35.7 (5.88) | 24.9 (1.76) | 27.2 (5.43) | <0.001 | |
| Nutritional Data | Dietary calcium (mg) | 1160 (629) | 1250 (426) | 1320 (464) | 1300 (742) | 0.938 |
| Dietary oxalate (mg) | 236 (316) | 331 (275) | 333 (323) | 212 (167) | 0.741 | |
| Ox/Ca ratio | 0.280 (0.233) | 0.275 (0.232) | 0.250 (0.196) | 0.184 (0.144) | 0.832 | |
| Dietary vitamin C | 80.4 (37.6) | 133 (152) | 152 (61.5) | 156 (129) | 0.249 | |
| Outcome | Fecal oxalate (uM/mg) | 0.240 (0.0944) | 0.932 (0.117) | 0.998 (0.140) | 0.742 (0.192) | <0.001 |
| Urinary oxalate (mg/24h) | 31.9 (7.73) | 62.5 (12.7) | 99.9 (57.0) | 33.8 (12.2) | <0.001 |
BMI, body mass index.
Data for body measurements, nutrition, and outcomes are presented as Mean (± SD).
∗
P-value from the ANOVA test for the continuous variables, and chi-squared test for the categorical variables.