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. 2024 May 31;10(6):2089–2100. doi: 10.1021/acsinfecdis.4c00094

Figure 1.

Figure 1

Synthesis and evaluation of two semisynthetic vaccine candidates targeting the capsular polysaccharide, glucuronoxylomannan (GXM), of C. neoformans. (a) Structure of motif 2 of GXM and the decasaccharide antigen. (b) Conjugation of glycan 1 to carrier proteins anthrax PA63 or CRM197. (c) Immunization schedule.