Table 4. Summary of Important In Vitro Peptide Parameters Measured in This Study.
| peptide designation and sequence | length | charge | antimicrobial | LPS binding | TNF-α inhibition | toxicity to macrophages | α-helix |
|---|---|---|---|---|---|---|---|
| K2(AL)8K2 | 20 | +5 | no | +++ | +++ | no | +++ |
| (AL)9K2 | 20 | +3 | no | + | + | no | + |
| K(AL)9K | 20 | +3 | no | + | + | no | ± |
| L(AL)9K | 20 | +2 | no | – | – | no | n |
| K(AL)3K(AL)2K(AL)3K | 20 | +5 | yes | ++ | + | yes | +++ |
| K2(AL)5AK2 | 15 | +5 | no | +++ | + | no | ++ |
| K2(AL)3K2 | 10 | +5 | no | – | – | no | ++ |