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. 2024 May 21;7(6):1795–1806. doi: 10.1021/acsptsci.4c00033

Table 4. Summary of Important In Vitro Peptide Parameters Measured in This Study.

peptide designation and sequence length charge antimicrobial LPS binding TNF-α inhibition toxicity to macrophages α-helix
K2(AL)8K2 20 +5 no +++ +++ no +++
(AL)9K2 20 +3 no + + no +
K(AL)9K 20 +3 no + + no ±
L(AL)9K 20 +2 no no n
K(AL)3K(AL)2K(AL)3K 20 +5 yes ++ + yes +++
K2(AL)5AK2 15 +5 no +++ + no ++
K2(AL)3K2 10 +5 no no ++