Table 2.
Regions showing significant differences in gFCD, lFCD, and sFCD among LSS, RSS, and HCs
| Regions | Hemisphere | MNI coordinates | Cluster size | F value | LSS vs. HCs | RSS vs. HCs | LSS vs. RSS | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| x | y | z | t value | Cohen’s d | t value | Cohen’s d | t value | Cohen’s d | ||||
| gFCD | ||||||||||||
| Inferior frontal gyrus | Left | − 45 | 27 | 3 | 39 | 11.29 | 4.61*** | 1.23 | 4.54*** | 1.17 | 0.50 | 0.15 |
| Supplementary motor area | Bilateral | 9 | 3 | 72 | 23 | 9.29 | 3.96*** | 1.02 | 4.24*** | 1.15 | − 0.32 | − 0.09 |
| lFCD | ||||||||||||
| Inferior frontal gyrus | Left | − 45 | 27 | 3 | 39 | 11.31 | 4.62*** | 1.23 | 4.53*** | 1.17 | 0.51 | 0.15 |
| Supplementary motor area | Bilateral | 9 | 3 | 72 | 22 | 9.27 | 3.98*** | 1.02 | 4.25*** | 1.15 | − 0.31 | − 0.09 |
| sFCD | ||||||||||||
| Cerebellum posterior lobe | Bilateral | 0 | − 54 | − 51 | 73 | 14.33 | − 3.77*** | − 0.99 | − 3.74*** | − 1.05 | 0.03 | 0.01 |
| Inferior frontal gyrus | Left | − 45 | 18 | 12 | 57 | 16.24 | 6.11*** | 1.57 | 4.43*** | 1.17 | 1.19 | 0.35 |
| Precentral gyrus | Left | 27 | ||||||||||
| Middle occipital gyrus | Left | − 24 | − 93 | 12 | 69 | 10.47 | − 3.84*** | − 0.99 | − 4.14*** | − 1.10 | 0.63 | 0.19 |
| Cerebellum anterior lobe | Bilateral | 3 | − 33 | − 21 | 37 | 12.39 | − 4.19*** | − 1.10 | − 3.67** | − 0.91 | − 1.11 | − 0.33 |
MNI Montreal Neurological Institute, LSS Left subcortical stroke, RSS Right subcortical stroke, HCs Healthy controls, gFCD global functional connectivity density, lFCD Long-range functional connectivity density, sFCD short-range functional connectivity density
*, 0.01 < P < 0.05; **, 0.001 < P < 0.01; ***, P < 0.001