Skip to main content
. 2024 Jun 3;15:1371463. doi: 10.3389/fimmu.2024.1371463
PMOP Postmenopausal osteoporosis
SOP Senile osteoporosis
IOP Idiopathic osteoporosis
WHO World health organization
BMD Bone mineral density
BMSCs Bone marrow mesenchymal stem cells
DNA Deoxyribonucleic acid
IL-1 Interleukin-1
IL-6 Interleukin-6
IL-17 Interleukin-17
TNF-α Tumor necrosis factor
OPG Osteoprotegerin
RANKL Receptor activator of nuclear factor-κB ligand
M-CSF Macrophage colony stimulating factor
AP-1 Activator protein 1
NF-κB Nuclear factor -κB
Erα Estrogen receptor-α
BCAR1 Breast cancer anti-estrogen resistance protein-1
BMP-4 Bone morphogenetic protein 4
SMAD Drosophila mothers against decapentaplegic protein
PTH Parathyroid hormone
OVX Ovariectomy
NLRP3 NOD-like receptor family pyrin domain-containing 3
TH-17 T helper cell 17
IL-18 Interleukin-18
IL-1β Interleukin-1β
PCD programmed cell death
Bcl-2 B-cell lymphoma-2;Bax, Bcl-2 associated X protein
Caspase Cysteine-aspartic protease
mTOR mammalian target of rapamycin
ATGs Autophagy-related proteins
GSH Glutathione
GPX4 Glutathione peroxidase 4
GCH1 GTP cyclohydrolase 1
DHFR Dihydrofolate reductase
BH4 Tetrahydrobiopterin
FSP1 Ferroptosis suppressor protein 1
NADPH Nicotinamide adenine dinucleotide phosphate
CoQ10 Coenzyme Q10
DHODH Dihydroorotate dehydrogenase
RIPK Receptor-interacting protein kinase
MLKL Mixed-lineage kinase domain-like protein
GSDM Gasdermin
HMGB1 High-mobility group box 1 protein
DAMPs Damage‐associated molecular patterns
PAMPs Pathogen-related molecular patterns
ROS Reactive oxygen species
PRRs Pattern recognition receptors
NLR NOD-like receptor
NLRP1 NLR family pyrin domain-containing 1
NLRC4 NLR family CARD domain containing 4
NRRC5 NLR family CARD domain containing 5
PYD Pyrindomain
AIM2 Absent in melanoma 2
LPS Lipopolysaccharide
PD-L1 Programmed death ligand 1
GZM Granzyme
GAS Group A Streptococcus
ASC Apoptosis-related speck-like protein
BMMs Bone marrow macrophages
rPTH recombinant human parathyroid hormone analog
UA Urolithin A
RA Rosmarinic acid
STZ streptozotocin
FNDC5 Fibronectin type III domain-containing 5
TCM Traditional Chinese Medicine
Nrf2 Nuclear factor erythroid 2-related factor 2
Keap1 Kelch-like ECH-associated protein-1.