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. Author manuscript; available in PMC: 2024 Aug 1.
Published in final edited form as: JACC Heart Fail. 2023 Mar 20;11(8 Pt 2):1103–1117. doi: 10.1016/j.jchf.2023.01.030

FIGURE 4.

FIGURE 4

Changes in Hemodynamics From Baseline to Peak Exercise in the EILAH and RELAH Groups

Changes in hemodynamics from baseline to peak exercise in the patients with resting PCWP <15 mm Hg (EILAH, shown in blue) and resting PCWP ≥15 mm Hg (RELAH, shown in red). Dots represent median values for each group. Patients with EILAH had lower right atrial (RA) pressure, lower PCWP, and lower PCWP-RA pressure gradient at rest. RA pressure increased comparably at peak exercise in both groups, whereas PCWP increased more in the EILAH groups. This resulted in nearly equivalent PCWP-RA pressure gradient at peak exertion in both groups. The peak PCWP is likely a major driver of symptoms, whereas the PCWP-RA pressure gradient is the main driver of left-to-right shunting. Abbreviations as in Figures 1 and 3.