Table 4.

β Variation Types, Electrophoresis Bands and Average Content of Globin Chain

β globin variant	β gene mutation	Amino acid changes	n	%	Zone and content %
Hb E	HBB:c.79G>A	26 (B8) Glu>Lys	50	72.5	Z(E),25.2
Hb New York	HBB:c.341T>A	113 (G15) Val>Glu	10	14.5	Z11,42.8
Hb J Bangkok	HBB:c.170G>A	56 (D7) Gly>Asp	2	2.9	Z12,46.7
Hb D-Punjab	HBB:c.364G>C	121 (GH4) Glu>Gln	1	1.5	Z(D),40.7
Hb J-Lome	HBB:c.180G>C	59 (E3) Lys>Asn	1	1.5	Z13,50.7
Hb G-Taipei	HBB:c.68A>G	22 (B4) Glu>Gly	1	1.5	Z(D),38.4
Hb G-Coushatta	HBB:c.68A>C	22 (B4) Glu>Ala	1	1.5	Z(D),40
Hb G-San José	HBB:c.23A>G	7 (A4) Glu>Gly	1	1.5	Z(F),31.9
Hb Hope	HBB:c.410G>A	136 (H14) Gly>Asp	1	1.5	Z10,35.2
Hb Mizuho	HBB:c.206T>C	68 (E12) Leu>Pro	1	1.5	Z(F),18.9