Figure 7.

Lung histopathology and inflammatory response is consistent with complement mediated disease. (A) Representative images of H&E staining of lung slides from histopathologic exam, with control and infected mice on 2 and 4 dpi which demonstrates cellular infiltrates (2 dpi) (black arrows) and edema (4 dpi) (black asterisks). n = 3 mice per time point. (B) Serum and lung cytokine profiling for 1–5 dpi, title above graph in each column indicates whether sample is from serum or lung homogenate. n = 3 mice per group at each time point. DMEM (Dulbecco’s Modified Eagle’s Medium), dpi = days post-infection. Significance determined by unpaired t-test, * p < 0.05.