Table 6-1. – Characteristics of participants with atrial fibrillation or flutter in the ELSA-Brasil baseline according to CHA 2 DS 2 -VASc scores.
| Atrial fibrillation or flutter | |||||||
|---|---|---|---|---|---|---|---|
| By ECG recording | By self-report only | All cases of AF or flutter | |||||
| CHA 2 DS 2 -VASc score < 2 (N=16) | CHA 2 DS 2 -VASc score ≥ 2 (N=32) | CHA 2 DS 2 -VASc score < 2 (N=130) | CHA 2 DS 2 -VASc score ≥ 2 (N=153) | CHA 2 DS 2 -VASc score < 2 (N=146) | CHA 2 DS 2 -VASc score ≥ 2 (N=185) | p-value | |
| Age (years; median [P25 - P75]) | 56.0 [49.5 – 61.2] | 67.5 [58.0 – 71.2] | 49.5 [45.0 – 56.0] | 59.0 [53.0 – 66.0] | 50.0 [45.0 – 57.0] | 60.0 [53.0 – 68.0] | <0.001 ‡ |
| Female sex (N (%)) | 3 (18.8%) | 15 (46.9%) | 60 (46.2%) | 97 (63.4%) | 63 (43.2%) | 112 (60.5%) | 0.002 † |
| Coronary artery disease (N (%)) | 0 (0.0%) | 7 (21.9%) | 2 (1.5%) | 64 (41.8%) | 2 (1.4%) | 71 (38.4%) | <0.001 † |
| Stroke (N (%)) | 0 (0.0%) | 1 (3.1%) | 0 (0.0%) | 7 (4.6%) | 0 (0.0%) | 8 (4.3%) | 0.010 ¥ |
| 10-year ASCVD risk > 10% (N (%)) | 7 (43.8%) | 16 (66.7%) | 15 (11.7%) | 26 (30.6%) | 22 (15.3%) | 42 (38.5%) | <0.001 † |
| Prior ASCVD or 10-year ASCVD risk > 10% | 7 (43.8%) | 24 (75.0%) | 17 (13.1%) | 94 (61.4%) | 24 (16.4%) | 118 (63.8%) | <0.001 † |
| Use of anticoagulants (N (%)) | 3 (18.8%) | 16 (50.0%) | 1 (0.8%) | 4 (2.6%) | 4 (2.7%) | 20 (10.8%) | 0.005 ¥ |
| Use of antiplatelet agents (N (%)) | 2 (12.5%) | 5 (15.6%) | 2 (1.5%) | 43 (28.1%) | 4 (2.7%) | 48 (25.9%) | <0.001 † |
The 10-year ASCVD risk is defined only in participants without prior coronary artery disease or stroke. AF: Atrial fibrillation; ASCVD: Atherosclerotic cardiovascular disease. P-values are presented for the comparison between the CHA 2 DS 2 -VASc score < 2 (N=146) and the CHA 2 DS 2 -VASc score ≥ 2 (N=185) groups among all cases of AF or flutter using.† Chi-squared, ‡ Mann-Whitney U or ¥ Fisher’s exact tests. Source: Santos et al. 202