TABLE 1.

MCC high genes DE comparison of MCC and SCLC showed that 16 genes had greater than 5 log fold‐change higher expression in MCC with FDR < 0.001.

Gene symbol	Fold‐change	p‐value	FDR	Gene name
NEFM	210.8	7.57E‐25	4.08E‐21	Neurofilament, medium polypeptide
TFAP2B	210.8	1.07E‐22	2.87E‐19	Transcription factor AP‐2 beta
ISL1	158.7	3.17E‐19	2.44E‐16	ISL LIM homeobox 1
NEFL	116.2	1.99E‐17	1.34E‐14	Neurofilament, light polypeptide
PEG3	76.1	2.73E‐09	4.88E‐08	Paternally expressed 3
MYO15A	73.5	7.48E‐21	8.07E‐18	Myosin XVA
MPPED2	69.6	1.17E‐14	2.26E‐12	Metallophosphoesterase domain containing 2
NHLH1	56.1	8.14E‐22	1.10E‐18	Nescient helix loop helix 1
KRT20	46.9	6.11E‐08	6.07E‐07	Keratin 20
SYN2	46.2	1.96E‐11	9.97E‐10	Synapsin II
POU4F1	42.2	1.38E‐10	4.34E‐09	POU class 4 homeobox 1
TFAP2A	37.8	1.23E‐16	4.73E‐14	Transcription factor AP‐2 alpha
LGALS7B	36.3	1.58E‐07	1.32E‐06	Lectin, galactoside‐binding, soluble, 7
POU4F3	35.3	1.88E‐19	1.69E‐16	POU class 4 homeobox 3
USH2A	32.2	6.35E‐06	3.12E‐05	Usher syndrome 2A
ADCY1	32.2	3.50E‐12	2.52E‐10	Adenylate cyclase 1

Note: These genes were designated as MCC high.