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. 2024 May 14;30(6):1739–1748. doi: 10.1038/s41591-024-02960-5

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a–l, Cognitive test scores for RT (a), SB (b), SI (c), SD (d), TMN (e), TMA (f), MX (g), WM (h), QZ (i), VY (j) and PR (k) and G4 and G6 scores (l) plotted against age. Lines of best fit with standard error are stratified by AD-PRS_APOE group (indicated by line color); The ‘high’ group is the top 5th percentile of AD-PRS_APOE and the ‘low’ group is the bottom 95th percentile of AD-PRS_APOE. The response time is the average time taken per item.